Op-Ed: To fight against COVID-19, vitamin D sufficiency must be prioritized
November 25, 2020
Vitamin D deficiency can lead to poor health outcomes. The deficiency has been associated with a large number of disorders such as metabolic syndrome and cancers, as well as autoimmune, psychiatric and neurodegenerative diseases. Many of these conditions correlate to higher rates and more severe cases of COVID-19. There is also a robust correlation to underlying metabolic health conditions such as obesity, high blood sugar and high blood pressure (of which all three are elements of metabolic syndrome), but there is growing evidence from labs and research around the globe that correlates vitamin D with severe COVID-19 outcomes.
Adequate serum vitamin D is apparently an important part of innate and adaptive immune function. While vitamin D insufficiency is an individual health problem, it is also a problem for our body politic. Vitamin D insufficiency causes undue strain on our healthcare system and on the economy during a pandemic. Public health policy might be well served by prioritizing adequate vitamin D levels in the population. This could improve health outcomes, reduce illness from infectious disease and reduce the overall effects of poor health in our society.
The epidemic of vitamin D deficiency in America is a compounding factor that wreaks havoc on our health and healthcare bureaucracy. A recent study in Boston found two-thirds of healthy young adults were vitamin D deficient by the end of winter, and around 60 percent of nursing home residents are deficient. Early in the pandemic, several population studies—including one in Israel and one in Chicago — linked low levels of vitamin D to poor health outcomes and heightened susceptibility for COVID-19.
While the exact nature of the causative role vitamin D deficiency plays in many of these conditions remains unclear, vitamin D supplementation can be a central strategy for the government to minimize the effects of the pandemic.
Vitamin D does not operate like most vitamin supplements. It is a fat soluble vitamin that is scarcely found in food. Produced in the skin from UVB sun exposure, it is transported to the liver and then to the kidney where it changes into a hormone. This hormone is responsible for increasing calcium transport from food into the gut and ensuring that calcium is adequate. However, like all hormones, it also has other functions, such as supporting immune pathways in the body.
The consequences of having very low vitamin D are dire, and high vitamin D levels have been proven to cause problems with digestion, although these levels are difficult to reach. It remains that around 35 percent of adults in the United States are vitamin D deficient, with much higher percentages in those at greatest risk from COVID-19. The best way to know the ideal dose is to monitor blood levels, but there are people who are highly likely to be deficient in vitamin D. These people should have vitamin D available to them as a part of combating the effect that COVID-19 has on our society.
In a 2017 study on the financial viability of vitamin D supplementation in a nursing home, researchers found that the provision of systematic vitamin D supplementation to nursing home residents would provide substantial net economic benefit to society. They also found that assessing vitamin D status before starting supplementation was not necessary for the patients that were particularly at risk for vitamin D deficiency.
There has not yet been placebo-controlled research, in which one group takes vitamin D and another does not, in regards to COVID-19. So, there is no clear evidence for causation. However, our government has been working to find a solution and a vaccine, and we have completely changed our lives to minimize the effect that COVID-19 has on our economy and health for the long term.
Ensuring that vitamin D is easily accessible could manifest in several ways, including an increase in accessible testing and distribution channels. Letting government and institutional subsidies support ways to easily obtain vitamin D blood tests and supplements is also a simple and cost-effective preventative measure that is likely to lower the impact from COVID-19, especially as we head into winter.
Robin Whittle • Nov 25, 2020 at 5:14 pm
For links to and discussion of the latest research on vitamin D and COVID-19, please see my sites https://VitaminDStopsCOVID.info and https://aminotheory.com/cv19/#lr . Please also see https://VitaminDWiki.com .
John Lambiase • Nov 25, 2020 at 3:54 pm
No Clinical Trial?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7456194/
https://pmj.bmj.com/content/early/2020/11/12/postgradmedj-2020-139065
Here is two.
Maybe if Researchers understood how to set up the trials around Vitamin D like Drug companies do around their products, maybe vitamin D can get a fair shake.
10mcgs is a joke and not remotely enough to put a dent in deficiency especially in winter.
Everyone is different. I know people taking 50,000 iu weekly and their D levels are barely 39 ng/mL and on the other end of the spectrum people taking 2000 iu daily and their vitamin D level is the same 39 ng/mL. There are too many variables for different people and that is why Trials need to be set up around a Therapeutic level in the middle of the normal range of 30-100 ng/mL. (preferably 40-60 ng-mL) rather than a single particular dosage whether that be a daily or weekly dose.
For me, I take 5000 iu daily and during the summer my level was a constant 58 ng/mL but right now last week it had fallen 10 points to 48 ng/mL probably due to change in winter sun angle of incidence. By the way Calcium levels are a constant 9.8 so no hypercalcemia here. I do not think medicine understands this and that is clear considering ineffective trial outcomes.
Consequently I live in Texas which is well below the 35 line of latitude. Would you like to guess what that means for people living above that line regarding winter UVB vitamin D synthesis. Try nonexistent. Good grief it was enough for my level to drop 10 points in two months at 5000 iu.